Iowa State 2025 Schedule
| Date | Opponent | Time/Score | Location | Media |
|---|---|---|---|---|
| Saturday, 23 August 2025 |  Kansas State |
Dublin W 24-21 |
Dublin Aviva Stadium (Dublin, Ireland) |
First Ranking |
| Saturday, 27 September 2025 |  Arizona |
W 39-14 | Iowa State (Ames, IA) |
|
| Saturday, 04 October 2025 |  Cincinnati |
L 30-38 | Cincinnati (Cincinnati, OH) |
|
| Saturday, 11 October 2025 |  Colorado |
L 17-24 | Iowa State (Ames, IA) |
|
| Saturday, 25 October 2025 |  Brigham Young |
L 27-41 | Iowa State (Ames, IA) |
Iowa State Review |
| Saturday, 01 November 2025 |  Arizona State |
L 19-24 | Iowa State (Ames, IA) |
|
| Saturday, 08 November 2025 |  Texas Christian University |
W 20-17 | TCU (Fort Worth, TX) |
|
| Saturday, 22 November 2025 |  Kansas |
W 38-14 | Iowa State (Ames, IA) |
|
| Saturday, 29 November 2025 |  Oklahoma St |
W 20-13 | Oklahoma ST (Stillwater, OK) |